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Hemostatic Matrix Offers Hope for Life-Threatening Liver Bleeding on the Battlefield








19 August 2024


A new study published in Military Medicine highlights the potential of the Silicone-Based Polymer (SBP) Universal Combat Matrix (UCM) to stop severe bleeding from noncompressible torso injuries. This lightweight, multifunctional dressing was tested in a model designed to simulate the severe bleeding caused by battlefield trauma, delivering remarkable results in controlling blood loss and promoting healing.


In the study, researchers used UCM to treat liver injuries in a preclinical model. The results showed:


  • Quick Bleeding Control: The UCM stopped bleeding in just over four minutes on average.

  • Durable Results: After 48 hours, all treated wounds remained stable, with no signs of re-bleeding.

  • Support for Healing: The UCM promoted the formation of stable blood clots and tissue regeneration, showing its ability to protect and heal wounds.


Why This Matters

Current methods to control bleeding, such as tourniquets and standard hemostatic agents, have limitations, particularly for injuries in areas that can’t be compressed. The SBP UCM addresses this gap with a lightweight, easy-to-carry dressing that could make a life-or-death difference for soldiers in combat and first responders in emergencies. This innovation comes at a time when the military is seeking advanced tools to improve survival rates in complex combat scenarios. The study's results suggest the UCM could be a game-changer, offering a reliable and versatile solution for treating injuries in austere and resource-limited environments. As a next milestone in its development, SiOxMed is preparing to pursue FDA 510(k) clearance for hemostatic indications.


About SiOxMed

SiOxMed is dedicated to advancing medical innovation through cutting-edge solutions for wound care and hemostasis. By collaborating with researchers, clinicians, and industry leaders, SiOxMed is shaping the future of trauma medicine.


Jorgensen AM, Hickerson WL, Paladino L. A Novel Approach to Noncompressible Torso Hemorrhage Using a Silicone-Based Polymer Universal Combat Matrix. Mil Med. 2024 Aug 19;189(Suppl 3):247-253. doi: 10.1093/milmed/usae085. PMID: 39160841.


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